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Korean Circ J. 2021;51(7):610-622.

Cost-Effectiveness Analysis of Hypertension Screening in the Korea National Health Screening Program.

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제1저자 이해영 · 교신저자 김태현

소속 (6)
  1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
  2. Cardiovascular and Metabolic Diseases Etiology Research Center, Yonsei University College of Medicine, Seoul, Korea.
  3. Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea.
  4. Division of Cardiology, College of Medicine, Catholic University of Korea, Seoul, Korea.
  5. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
  6. Department of Healthcare Management, Graduate School of Public Health, Yonsei University, Seoul, Korea. THKIM@yuhs.ac.

Abstract

BACKGROUND AND OBJECTIVES To evaluate the cost-effectiveness of routine hypertension (HTN) screening as a part of the national health-screening program.

METHODS Two aspects of cost-effectiveness were examined using the national general health-screening program. First, the cost of case-finding was computed for 5-year interval age groups. Second, the cost per quality adjusted life years (QALYs) gained were estimated for 12 different scenarios varying examination starting age, pattern and interval compared with no screening.

RESULTS The cost of finding one new HTN case was low as 26,284 Korean won (KRW) (approximately [approx.] United States Dollar 21) for 70-79 years old to as high as 70,552 KRW for 40-44 years old. Compared with no screening, the costs per QALYs of the following screening strategies were below the incremental cost-effectiveness ratio threshold (approx. KRW 30.5 million): first screening examination with the second confirmatory examination in adults aged ≥40 years every 3 years (KRW 10.2 million), every 2 years (KRW 13.2 million), or annually (KRW 19.9 million). One-way sensitivity analyses suggest that the results were mostly influenced by the sensitivity of the first screening examination, followed by the examination rate of the second confirmatory examination.

CONCLUSIONS HTN screening as a part of routine national health screening program was cost-effective for adults aged 40 years or older. The most cost-effective HTN screening strategy was the first screening examination with the second confirmatory examination in aged 40 years or older every 3 years.

Copyright © 2021. The Korean Society of Cardiology.

Keywords

Cost analysisHypertensionScreening

Figures

Figure 1
Figure 1 Decision tree and Markov model for estimating the cost-effectiveness of screening for HTN. (A) Structure of the decision tree with the single screening examination only. (B) Structure of the decision tree with the first screening examination and the second confirmatory examination. (C) Different health status in the Markov model. CKD = chronic kidney disease; HTN = hypertension; MI = myocardial infarction.
Figure 2
Figure 2 ICER of 21 different strategies for hypertension screening. ICER = incremental cost-effectiveness ratio; QALY = quality adjusted life year.
Figure 3
Figure 3 One-way sensitivity analysis tornado plot of strategy with the first screening examination and the second confirmatory examination for the general adults over 40 years old per 2 years versus strategy with no screening. ICER = the incremental cost-effectiveness ratio.

그림 출처: PubMed Central 공개 논문 (PMC8263297)

Conflict of interest statement

The authors have no financial conflicts of interest.

그 밖의 정보
출판 형태
Journal Article
저널
Korean circulation journal · ISSN 1738-5520
전자 출판
2021-05-14
연구비
Korea Centers for Disease Control and Prevention 2015-E33006-00
참고문헌
35편