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Age Ageing. 2022;51(3):6540143.

Analysis of blood pressure and blood pressure variability pattern among older patients in long-term care hospitals: an observational study analysing the Health-RESPECT (integrated caRE Systems for elderly PatiEnts using iCT) dataset.

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제1저자 최정연 · 교신저자 김광일

PMID 35253050 DOI 10.1093/ageing/afac018 IF 7.4 노인병내과
소속 (7)
  1. Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
  2. Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea.
  3. Institute of Health and Environment, Seoul National University, Seoul, Republic of Korea.
  4. Institute on Aging, Seoul National University, Seoul, Republic of Korea.
  5. Department of Environmental Health, Korea National Open University, Seoul, Republic of Korea.
  6. Healthcare ICT Research Center, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
  7. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.

Abstract

OBJECTIVES There are limited data regarding blood pressure (BP) variability among older adults living in long-term care hospitals (LTCHs). We aimed to collect data from LTCH and analyse BP characteristics and its variability among these patients using a novel platform.

METHODS The Health-RESPECT (integrated caRE Systems for elderly PatiEnts using iCT) platform was used to construct a daily BP dataset using data of 394 older patients from 6 LTCHs. BP variability was expressed as coefficient of variation (CV = standard deviation/mean of BP × 100). Physical frailty and cognitive function were evaluated using the K-FRAIL questionnaire and the Cognitive Performance Scale of the interRAI Long-Term Care Facilities tool, respectively.

RESULTS From September 2019 to September 2020, 151,092 BP measurements, 346.5 (IQR 290.8-486.3) measurements per patient, were included. The mean BP was 123.4 ± 10.8/71.3 ± 6.5 mmHg. BP was significantly lower in frail patients (122.2 ± 11.3/70.4 ± 6.8 mmHg) than in pre-frail/robust patients (124.4 ± 10.4/72.1 ± 6.1 mmHg, P < 0.05). However, CV of systolic (10.7 ± 2.3% versus 11.3 ± 2.3%, P = 0.005) and diastolic (11.6 ± 2.3% versus 12.4 ± 2.4%, P < 0.001) BP was higher in frail patients. The mean BP was lower, but BP variability was higher in patients with cognitive impairment. The mean BP, but not BP variability, was higher in treated hypertensive patients, as the number of antihypertensive medications increased.

CONCLUSION Older patients with physical or cognitive frailty had lower BP but higher BP variability. Relationship among frailty, increased BP variability and adverse clinical outcomes should be investigated.

© The Author(s) 2022. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Keywords

blood pressurefrailtyhypertensionlong-term careolder people

그 밖의 정보
출판 형태
Journal Article, Observational Study, Research Support, Non-U.S. Gov't
저널
Age and ageing · eISSN 1468-2834
MeSH
Aged · Antihypertensive Agents / therapeutic use · Blood Pressure · Delivery of Health Care, Integrated* · Frailty* / drug therapy / therapy · Hospitals · Humans · Hypertension* / diagnosis / drug therapy · Long-Term Care
Substances
Antihypertensive Agents