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BMJ Open. 2015;5(11):e008416.

Healthcare utilisation by pregnant patients with asthma in South Korea: a cohort study using nationwide claims data.

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제1저자 이창훈 · 교신저자 윤호일

소속 (7)
  1. Division for Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Republic of Korea, Seoul, Republic of Korea Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
  2. Division for Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Republic of Korea, Seoul, Republic of Korea.
  3. Division for Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Republic of Korea, Seoul, Republic of Korea Department of Information Statistics, College of Natural Science, Andong National University, Andong, Republic of Korea.
  4. Division for Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Republic of Korea, Seoul, Republic of Korea Real Estate R&D Institute, Korea Appraisal Board, Daegu, Republic of Korea.
  5. Department of Obstetrics and Gynecology, Seoul National University College of College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
  6. Division for Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Republic of Korea, Seoul, Republic of Korea Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
  7. Division for Healthcare Technology Assessment Research, National Evidence-based Healthcare Collaborating Agency, Seoul, Republic of Korea, Seoul, Republic of Korea Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam-Si, Republic of Korea.

Abstract

OBJECTIVES Few nationwide population-based studies have examined the burden of asthma during pregnancy. Here, we investigated the burden and medical treatment of asthma during pregnancy requiring healthcare utilisation in South Korea.

DESIGN Cohort study.

SETTING Nationwide insurance claims database.

PARTICIPANTS A total of 1,306,281 pregnant women who delivered in South Korea in 2009-2011.

OUTCOMES The prevalence and exacerbation rates of asthma requiring healthcare utilisation, and the prescription of antiasthmatic drugs during pregnancy.

RESULTS The prevalence of asthma requiring healthcare utilisation was 0.43% among pregnant women. Among those with asthma requiring healthcare utilisation, 6.9% were hospitalised and treated with systemic steroids and short-acting β2-agonists during pregnancy. Oral drugs were prescribed less during the third trimester than during the first trimester (all p values for trends were <0.001). A significant number of patients with asthma were likely to stop taking antiasthmatic drugs after becoming pregnant.

CONCLUSIONS The prevalence of asthma requiring healthcare utilisation during pregnancy was not very high. However, a significant number of women were likely to stop taking antiasthmatic drugs, and those who did tended to experience exacerbations.

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Keywords

EPIDEMIOLOGYinhaled respiratory drugspregnancy

그 밖의 정보
출판 형태
Journal Article, Research Support, Non-U.S. Gov't
저널
BMJ open · eISSN 2044-6055
전자 출판
2015-11-06
MeSH
Administration, Inhalation · Adrenal Cortex Hormones / therapeutic use · Adrenergic beta-Agonists / therapeutic use · Adult · Anti-Asthmatic Agents / therapeutic use · Asthma / drug therapy / epidemiology · Cohort Studies · Databases, Factual · Drug Prescriptions / statistics & numerical data · Drug Therapy, Combination · Female · Hospitalization / statistics & numerical data · Humans · Patient Acceptance of Health Care / statistics & numerical data · Pregnancy · Pregnancy Complications / drug therapy / epidemiology · Pregnancy Trimesters · Republic of Korea
Substances
Adrenal Cortex Hormones · Adrenergic beta-Agonists · Anti-Asthmatic Agents
참고문헌
25편