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Int J Epidemiol. 2018;47(1):289-298.

Association between adult height, myocardial infarction, heart failure, stroke and death: a Korean nationwide population-based study.

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제1저자 박찬순 · 교신저자 최의근

PMID 29025084 DOI 10.1093/ije/dyx175 IF 5.7 순환기내과
소속 (5)
  1. Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
  2. Department of Biostatistics, College of Medicine, Catholic University of Korea, Seoul, Republic of Korea.
  3. Division of Cardiology, Department of Internal Medicine, Soonchunhyang University Hospital, Seoul, Republic of Korea.
  4. Division of Cardiology, Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.
  5. Division of Cardiology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

Abstract

BACKGROUND The association between adult height and cardiovascular (CV) events and mortality has been suggested, albeit inconsistently. We sought to discover the comprehensive relationship between height, CV-related morbidity and all-cause death according to age.

METHODS We investigated the association between adult height and myocardial infarction (MI), heart failure (HF), stroke incidence and mortality in 16 528 128 Korean patients who underwent regular health check-ups (2005-08). Height was stratified by decile according to age (20-39 years, 40-59 years and ≥60 years) and gender.

RESULTS During a 9-year follow-up period, 590 346 participants died and 232 093 were admitted to hospital for MI, 201 411 for HF and 267 566 for stroke. An inverse relationship between height and MI, HF, stroke and all-cause death was observed in the overall cohort analysis. The association was unchanged after adjusting for CV risk and behavioural and adulthood socioeconomic factors. Both male and female sex showed an inverse relationship with height in adulthood, CV events and mortality. Adult height showed an inverse association in all CV events and mortality, especially in the older groups (≥40 years). In a subgroup analysis of body mass index, there was an inverse relationship between height, CV events and mortality in each group.

CONCLUSIONS Shorter height in adulthood was strongly related to an increased risk of MI, HF, stroke and all-cause death. A suitable environment and appropriate nutrition early in life could influence adult height and eventually reduce the risk of CV events and mortality.

© The Author 2017; all rights reserved. Published by Oxford University Press on behalf of the International Epidemiological Association

그 밖의 정보
출판 형태
Journal Article, Research Support, Non-U.S. Gov't
저널
International journal of epidemiology · eISSN 1464-3685
MeSH
Adult · Age Distribution · Aged · Aged, 80 and over · Body Height* · Cause of Death · Cohort Studies · Female · Heart Failure / epidemiology · Hospitalization · Humans · Incidence · Male · Middle Aged · Mortality* · Multivariate Analysis · Myocardial Infarction / epidemiology · Proportional Hazards Models · Republic of Korea / epidemiology · Risk Factors · Sex Distribution · Stroke / epidemiology · Young Adult