SCI 발표논문

SCI 발표논문

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Diabetes Care. 2010;33(7):1652-4.

Sarcopenic obesity: prevalence and association with metabolic syndrome in the Korean Longitudinal Study on Health and Aging (KLoSHA).

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제1저자 임수 · 교신저자 장학철

PMID 20460442 PMC2890376 DOI 10.2337/dc10-0107 IF 22.6 내분비대사내과
소속 (1)
  1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

Abstract

OBJECTIVE We investigated the prevalence of sarcopenic obesity (SO) and its relationship with metabolic syndrome in a community-based elderly cohort in Korea.

RESEARCH DESIGN AND METHODS In this study, 287 men and 278 women aged 65 or older were recruited. Sarcopenia was defined as the appendicular skeletal muscle mass (ASM) divided by height squared (Ht(2)) (kg/m(2)) or by weight (Wt) (%) of <1 SD below the sex-specific mean for young adults. Obesity was defined as a visceral fat area >or=100 cm(2).

RESULTS The prevalence of SO was 16.7% in men and 5.7% in women with sarcopenia defined by ASM/Ht(2); however, it was 35.1% in men and 48.1% in women by ASM/Wt. Using ASM/Wt, the homeostasis model assessment of insulin resistance of subjects with SO was higher and they were at higher risk for metabolic syndrome (odds ratio [OR] 8.28 [95% CI 4.45-15.40]) than the obese (5.51 [2.81-10.80]) or sarcopenic group (2.64 [1.08-6.44]).

CONCLUSIONS SO defined by ASM/Wt was more closely associated with metabolic syndrome than either sarcopenia or obesity alone.

그 밖의 정보
출판 형태
Journal Article, Research Support, Non-U.S. Gov't
저널
Diabetes care · eISSN 1935-5548
전자 출판
2010-05-11
MeSH
Aged · Aged, 80 and over · Aging* · Asian People / statistics & numerical data · Female · Humans · Insulin Resistance · Logistic Models · Longitudinal Studies · Male · Metabolic Syndrome / ethnology · Obesity / ethnology · Prevalence · Republic of Korea / epidemiology · Risk Factors · Sarcopenia / ethnology · Sex Distribution
참고문헌
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