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Hernia. 2020;24(3):481-488.

Prognosis of surgical hernia repair in cirrhotic patients with refractory ascites.

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제1저자 김선웅 · 교신저자 김윤준

소속 (6)
  1. Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
  2. Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine, Seoul, South Korea.
  3. Department of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea.
  4. Department of Surgery, Seoul National University College of Medicine, Seoul, South Korea.
  5. Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea. yoonjun@snu.ac.kr.
  6. Department of Internal Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, South Korea. yoonjun@snu.ac.kr.

Abstract

BACKGROUND Abdominal wall hernias are common in patients with ascites. Elective surgical repair is recommended for the treatment of abdominal wall hernias. However, surgical hernia repair in cirrhotic patients with refractory ascites is controversial. In this study, we aimed to evaluate the outcomes of elective surgical hernia repair in patients with liver cirrhosis with and without refractory ascites.

METHOD From January 2005 to June 2018, we retrospectively reviewed the records of consecutive patients with liver cirrhosis who underwent a surgical hernia repair.

RESULTS This study included 107 patients; 31 patients (29.0%) had refractory ascites. Preoperatively, cirrhotic patients with refractory ascites had a higher median model for end-stage liver disease (MELD) score (13.0 vs 11.0, P = 0.001) than those without refractory ascites. The 30-day mortality rate (3.2% vs 0%, P = 0.64) and the risk of recurrence (hazard ratio 0.410; 95% CI 0.050-3.220; P = 0.39) did not differ significantly between cirrhotic patients with refractory ascites and cirrhotic patients without refractory ascites. Among cirrhotic patients with refractory ascites, albumin (P = 0.23), bilirubin (P = 0.37), creatinine (P = 0.97), and sodium levels (P = 0.35) did not change significantly after surgery.

CONCLUSION In advanced liver cirrhosis patients with refractory ascites, hernias can be safely treated with elective surgical repair. Mortality rate within 30 days did not differ by the presence or absence of refractory ascites. Elective hernia repair might be beneficial for treatment of abdominal wall hernia in cirrhotic patients with refractory ascites.

Keywords

Hernia repairLiver cirrhosisRefractory ascites

그 밖의 정보
출판 형태
Journal Article, Research Support, Non-U.S. Gov't
저널
Hernia : the journal of hernias and abdominal wall surgery · eISSN 1248-9204
전자 출판
2019-09-11
MeSH
Aged · Ascites* / etiology / mortality · Elective Surgical Procedures / adverse effects · Female · Hernia, Ventral / complications / mortality / surgery · Herniorrhaphy* / adverse effects / methods / mortality · Humans · Liver Cirrhosis* / complications / mortality · Male · Middle Aged · Prognosis · Recurrence · Retrospective Studies · Surgical Mesh · Treatment Outcome
참고문헌
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