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Clin Mol Hepatol. 2017;23(3):205-211.

Current status and strategies for hepatitis B control in Korea.

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제1저자 조은주 · 교신저자 김윤준

소속 (6)
  1. Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea.
  2. Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
  3. Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea.
  4. Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
  5. Department of Internal Medicine, Soonchunhyang University Hospital, Seoul, Korea.
  6. Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.

Abstract

Hepatitis B virus (HBV) infection is the most common cause of chronic liver diseases in Korea. After the introduction of the universal HBV vaccination program, the prevalence of hepatitis B surface antigen was markedly reduced, and Korea is now classified as an area of intermediate endemicity for HBV. However, there are still hurdles for elimination of hepatitis B, such as immunoprophylaxis failure against vertical transmission, occurrence of acute hepatitis B among peoples who did not have vaccination at younger age, and rapid increase of immigrant populations from HBV endemic areas. To achieve the World Health Organization goal of viral hepatitis elimination by 2030 in Korea, we suggest comprehensive policies for more effective control of hepatitis B as following: i) insurance coverage for antiviral prophylaxis in mothers with high viremia, ii) screening for hepatitis B seromarkers and catch-up HBV vaccinations of susceptible persons with hepatitis B, iii) establishment of an independent 'viral hepatitis sector' in Centers for Disease Control & Prevention to organize and execute comprehensive strategy for management of viral hepatitis, iv) encourage of management of HBV infection in immigrant populations, v) national campaign to promote awareness of hepatitis B.

Keywords

Hepatitis BKoreaViral hepatitis

Figures

Figure 1.
Figure 1. Prevalence of HBsAg by age and sex group. Adopted from Korean National Health and Nutritional Examination Survey in 2014.
Figure 2.
Figure 2. A nationwide seroprevalence of HBsAg in 2009, Korea. Presented in 18th annual meeting of the Korean Association for the study of the Liver.
Figure 3.
Figure 3. Age distribution of acute hepatitis B. Adopted from the Korean Journal of Hepatology; 2011 [5].
Figure 4.
Figure 4. Korean program for implementing perinatal transmission prevention. Source: Korea Centers for Disease Control and Prevention (2016).
Figure 5.
Figure 5. Trends in the prevalence of HBV infection according to implementation of national HBV vaccination program. Source: Korea Centers for Disease Control and Prevention (2016). HBV, hepatitis B virus.

그림 출처: PubMed Central 공개 논문 (PMC5628005)

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts to disclose.

그 밖의 정보
출판 형태
Journal Article, Review
저널
Clinical and molecular hepatology · eISSN 2287-285X
전자 출판
2017-09-19
MeSH
Antiviral Agents / therapeutic use · Emigrants and Immigrants · Female · Hepatitis B / drug therapy / epidemiology / prevention & control · Humans · Pregnancy · Prevalence · Republic of Korea / epidemiology
Substances
Antiviral Agents
참고문헌
10편