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Emerg Infect Dis. 2014;20(10):1708-11.

Human granulocytic anaplasmosis, South Korea, 2013.

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제1저자 김계형 · 교신저자 오명돈

PMID 25271737 PMC4193166 DOI 10.3201/eid2010.131680 IF 7.9 감염내과

Abstract

We report a patient with human granulocytic anaplasmosis in South Korea. The patient had fever and thrombocytopenia. Human granulocytic anaplasmosis was confirmed by seroconversion, PCR, and sequence analysis for Anaplasma phagocytophilum. Morulae were observed in the cultured HL-60 cells inoculated with blood from the patient.

Figures

Figure 1
Figure 1 Phylogenetic trees for partial 16S rRNA gene sequences of an Anaplasma phagocytophilum isolate obtained from a patient with human granulocytic anaplasmosis in South Korea (black dots) and those of the A. phagocytophilum strains reported from A) South Korea and B) other countries. Trees were constructed by using the neighbor-joining method. Locations (country/province or city), hosts, and GenBank accession numbers are indicated. Branch lengths of trees show evolutionary distances. Scale bars indicate 1.0% sequence distance. KWD, Korean water deer.
Figure 2
Figure 2 Light micrograph of Anaplasma phagocytophilum cultured in human promyelocytic cell line HL-60, showing A. phagocytophilum morulae as basophilic and intracytoplasmic inclusions (arrows). Wright–Giemsa stain, original magnification x1,000.

그림 출처: PubMed Central 공개 논문 (PMC4193166)

그 밖의 정보
출판 형태
Case Reports, Journal Article
저널
Emerging infectious diseases · eISSN 1080-6059
MeSH
Adrenergic alpha-Agonists / administration & dosage / therapeutic use · Anaplasma phagocytophilum / genetics / isolation & purification · Anaplasmosis / epidemiology · Anti-Bacterial Agents / administration & dosage / therapeutic use · Ceftriaxone / administration & dosage / therapeutic use · Doxycycline / administration & dosage / therapeutic use · Female · Humans · Middle Aged · Norepinephrine / administration & dosage / therapeutic use · Phylogeny · Republic of Korea / epidemiology
Substances
Adrenergic alpha-Agonists · Anti-Bacterial Agents · Ceftriaxone · Doxycycline · Norepinephrine
참고문헌
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