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J Clin Hypertens (Greenwich). 2017;19(6):620-626.

Association between reduced arterial stiffness and preserved diastolic function of the left ventricle in middle-aged and elderly patients.

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제1저자 박경택, 김학령 · 교신저자 조주희

소속 (2)
  1. Department of Internal Medicine, Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.
  2. Department of Biostatistics, Boramae Medical Center, Seoul, Korea.

Abstract

The aim of this study was to investigate whether arterial stiffness plays a role in retaining normal diastolic function in a middle-aged and elderly Korean population. A total of 267 patients without documented cardiovascular disease, 50 years and older (mean age, 57.3±6.3 years; 69.8% men) were retrospectively analyzed. All patients underwent both transthoracic echocardiography and brachial-ankle pulse wave velocity measurement on the same day. Patients with septal annular peak velocity (e') ≥8 cm/s and left atrial volume index <34 mL/m2 were considered as having normal diastolic function. Ninety-eight patients (36.7%) had normal diastolic function. Low brachial-ankle pulse wave velocity (<1314 cm/s) was an independent factor for determining normal diastolic function even after controlling for potential confounders in multiple logistic regression analysis (odds ratio, 2.58; 95% confidence interval, 1.46-4.57; P=.001). Our results suggest that compliant arteries may play an important role in maintaining normal left ventricular diastolic function in middle-aged and elderly patients without documented cardiovascular disease.

©2017 Wiley Periodicals, Inc.

Keywords

arterial stiffnessdiastolic functionelderlypulse wave velocity

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

그 밖의 정보
출판 형태
Journal Article
저널
Journal of clinical hypertension (Greenwich, Conn.) · eISSN 1751-7176
전자 출판
2017-02-13
MeSH
Ankle Brachial Index · Diastole / physiology · Echocardiography / methods · Female · Heart Ventricles / diagnostic imaging · Humans · Male · Middle Aged · Pulse Wave Analysis / methods · Republic of Korea / epidemiology · Retrospective Studies · Vascular Stiffness / physiology · Ventricular Dysfunction, Left / complications / diagnosis / epidemiology / physiopathology · Ventricular Function, Left / physiology
참고문헌
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