J Clin Hypertens (Greenwich). 2017;19(6):620-626.
Association between reduced arterial stiffness and preserved diastolic function of the left ventricle in middle-aged and elderly patients.
제1저자 박경택, 김학령 · 교신저자 조주희
소속 (2)
- Department of Internal Medicine, Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.
- Department of Biostatistics, Boramae Medical Center, Seoul, Korea.
Abstract
The aim of this study was to investigate whether arterial stiffness plays a role in retaining normal diastolic function in a middle-aged and elderly Korean population. A total of 267 patients without documented cardiovascular disease, 50 years and older (mean age, 57.3±6.3 years; 69.8% men) were retrospectively analyzed. All patients underwent both transthoracic echocardiography and brachial-ankle pulse wave velocity measurement on the same day. Patients with septal annular peak velocity (e') ≥8 cm/s and left atrial volume index <34 mL/m2 were considered as having normal diastolic function. Ninety-eight patients (36.7%) had normal diastolic function. Low brachial-ankle pulse wave velocity (<1314 cm/s) was an independent factor for determining normal diastolic function even after controlling for potential confounders in multiple logistic regression analysis (odds ratio, 2.58; 95% confidence interval, 1.46-4.57; P=.001). Our results suggest that compliant arteries may play an important role in maintaining normal left ventricular diastolic function in middle-aged and elderly patients without documented cardiovascular disease.
©2017 Wiley Periodicals, Inc.
Keywords
arterial stiffnessdiastolic functionelderlypulse wave velocity
Comment · 정정
Conflict of interest statement
The authors declare that they have no conflicts of interest.
그 밖의 정보
- 출판 형태
- Journal Article
- 저널
- Journal of clinical hypertension (Greenwich, Conn.) · eISSN 1751-7176
- 전자 출판
- 2017-02-13
- MeSH
- Ankle Brachial Index · Diastole / physiology · Echocardiography / methods · Female · Heart Ventricles / diagnostic imaging · Humans · Male · Middle Aged · Pulse Wave Analysis / methods · Republic of Korea / epidemiology · Retrospective Studies · Vascular Stiffness / physiology · Ventricular Dysfunction, Left / complications / diagnosis / epidemiology / physiopathology · Ventricular Function, Left / physiology
- 참고문헌
- 37편