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J Neurogastroenterol Motil. 2013;19(4):433-53.

Abdominal bloating: pathophysiology and treatment.

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제1저자 서아영 · 교신저자 김나영

소속 (1)
  1. Department of Internal Medicine, Seoul National University, Bundang Hospital, Seongnam, Gyeonggi-do, Korea.

Abstract

Abdominal bloating is a very common and troublesome symptom of all ages, but it has not been fully understood to date. Bloating is usually associated with functional gastrointestinal disorders or organic diseases, but it may also appear alone. The pathophysiology of bloating remains ambiguous, although some evidences support the potential mechanisms, including gut hypersensitivity, impaired gas handling, altered gut microbiota, and abnormal abdominal-phrenic reflexes. Owing to the insufficient understanding of these mechanisms, the available therapeutic options are limited. However, medical treatment with some prokinetics, rifaximin, lubiprostone and linaclotide could be considered in the treatment of bloating. In addition, dietary intervention is important in relieving symptom in patients with bloating.

Keywords

BloatingPathophysiologyRifaximinTherapy

Figures

Figure 1
Figure 1 Luminal and mucosal colonic microbiota and their roles in gut homeostasis. Modified from Parkes et al.35
Figure 2
Figure 2 Potential mechanisms behind bloating and visible distension in functional gastrointestinal disorders. Modified from Simrén.168 CNS, central nervous system; ENS, enteric nervous system; GI, gastrointestinal.

그림 출처: PubMed Central 공개 논문 (PMC3816178)

Conflict of interest statement

Conflicts of interest: None.

그 밖의 정보
출판 형태
Journal Article, Review
저널
Journal of neurogastroenterology and motility · ISSN 2093-0879
전자 출판
2013-10-07
참고문헌
178편