PLoS One. 2021;16(7):e0254704.
Fully automated waist circumference measurement on abdominal CT: Comparison with manual measurements and potential value for identifying overweight and obesity as an adjunct output of CT scan.
제1저자 주이진, 곽민선 · 교신저자 윤순호
소속 (3)
- Department of Radiology, Seoul National University Hospital and Seoul National Collage of Medicine, Seoul, Korea.
- Department of Internal Medicine, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Korea.
- Department of Research and Development, MEDICALIP Co. Ltd., Seoul, Korea.
Abstract
OBJECTIVE Waist circumference (WC) is a widely accepted anthropometric parameter of central obesity. We investigated a fully automated body segmentation algorithm for measuring WC on abdominal computed tomography (CT) in comparison to manual WC measurements (WC-manual) and evaluated the performance of CT-measured WC for identifying overweight/obesity.
MATERIALS AND METHODS This retrospective study included consecutive adults who underwent both abdominal CT scans and manual WC measurements at a health check-up between January 2013 and November 2019. Mid-waist WCs were automatically measured on noncontrast axial CT images using a deep learning-based body segmentation algorithm. The associations between CT-measured WC and WC-manual was assessed by Pearson correlation analysis and their agreement was assessed through Bland-Altman analysis. The performance of these WC measurements for identifying overweight/obesity (i.e., body mass index [BMI] ≥25 kg/m2) was evaluated using receiver operating characteristics (ROC) curve analysis.
RESULTS Among 763 subjects whose abdominal CT scans were analyzed using a fully automated body segmentation algorithm, CT-measured WCs were successfully obtained in 757 adults (326 women; mean age, 54.3 years; 64 women and 182 men with overweight/obesity). CT-measured WC was strongly correlated with WC-manual (r = 0.919, p < 0.001), and showed a mean difference of 6.1 cm with limits of agreement between -1.8 cm and 14.0 cm in comparison to WC-manual. For identifying overweight/obesity, CT-measured WC showed excellent performance, with areas under the ROC curve (AUCs) of 0.960 (95% CI, 0.933-0.979) in women and 0.909 (95% CI, 0.878-0.935) in men, which were comparable to WC-manual (AUCs of 0.965 [95% CI, 0.938-0.982] and 0.916 [95% CI, 0.886-0.941]; p = 0.735 and 0.437, respectively).
CONCLUSION CT-measured WC using a fully automated body segmentation algorithm was closely correlated with manually-measured WC. While radiation issue may limit its general use, it can serve as an adjunctive output of abdominal CT scans to identify overweight/obesity.
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그림 출처: PubMed Central 공개 논문 (PMC8289071)
Conflict of interest statement
D.H.P. is an employee of MEDICAL IP, Co. Ltd.; and S.H.Y. is a chief medical officer of MEDICAL IP, Co. Ltd. and owns stock options of the company: I.J. and M.S.K have declared that no competing interests exist. This does not alter our adherence to PLOS ONE policies on sharing data and materials. There are no patents, products in development or marketed products associated with this research to declare.
그 밖의 정보
- 출판 형태
- Journal Article, Research Support, Non-U.S. Gov't
- 저널
- PloS one · eISSN 1932-6203
- 전자 출판
- 2021-07-19
- MeSH
- Abdomen / diagnostic imaging · Adult · Aged · Aged, 80 and over · Anthropometry · Body Mass Index · Female · Four-Dimensional Computed Tomography* · Humans · Male · Middle Aged · Obesity / diagnosis / diagnostic imaging / epidemiology · Overweight / diagnosis / diagnostic imaging / epidemiology · Waist Circumference · Young Adult
- 참고문헌
- 22편