BMC Pulm Med. 2016;16(1):151.
The regional association between bronchiectasis and lung cancer in chest CT.
제1저자 김연욱 · 교신저자 김덕겸
소속 (4)
- Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
- Department of Radiology, Seoul National University College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
- Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, 20 Boramaero-5-Gil, Dongjak-Gu, Seoul, 156-707, Republic of Korea.
- Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, 20 Boramaero-5-Gil, Dongjak-Gu, Seoul, 156-707, Republic of Korea. kimdkmd@snu.ac.kr.
Abstract
BACKGROUND Limited studies have examined the association between lung cancer and bronchiectasis (BE). This study evaluated the regional association between BE and lung cancer by analyzing the lobar location of lung cancer in patients with underlying BE.
METHODS This clustered multi-level study enrolled patients who had underlying BE and were newly diagnosed with lung cancer between January 1, 2010 and May 30, 2013 in two referral hospitals in South Korea. By analyzing the presence of lung cancer and underlying BE as event variables at the level of lung lobes on chest computed tomography (CT), we evaluated the association of BE and lung cancer by the locations of the diseases.
RESULTS Eighty-one patients with BE and combined lung cancer were enrolled. Within 486 lung lobes of the patients, combined BE and lung cancer in the same lobe was found in 11 lobes (2.3 %). Using the general estimating equation assuming BE as a risk factor of lung cancer, the results indicated that the prevalence of lung cancer was significantly lower in the lobes with pre-existing BE (β = -1.09, p-value = 0.001).
CONCLUSIONS Regionally, pre-existing BE was associated with a lower risk of the occurrence of lung cancer in the same lobe.
Keywords
BronchiectasisChest CTLung cancerLung lobesRegional association
Figures
그림 출처: PubMed Central 공개 논문 (PMC5111282)
그 밖의 정보
- 출판 형태
- Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't
- 저널
- BMC pulmonary medicine · eISSN 1471-2466
- 전자 출판
- 2016-11-15
- MeSH
- Aged · Bronchiectasis / complications / diagnostic imaging · Female · Humans · Lung / diagnostic imaging / physiopathology · Lung Neoplasms / complications / diagnostic imaging · Male · Middle Aged · Republic of Korea · Retrospective Studies · Smoking / adverse effects · Tomography, X-Ray Computed
- 참고문헌
- 22편