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PLoS One. 2015;10(2):e0117582.

Not early referral but planned dialysis improves quality of life and depression in newly diagnosed end stage renal disease patients: a prospective cohort study in Korea.

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제1저자 박지인, 김명희 · 교신저자 이정표

소속 (9)
  1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; Clinical Research Center of End Stage Renal Disease in Korea, Daegu, Korea.
  2. Clinical Research Center of End Stage Renal Disease in Korea, Daegu, Korea; Department of Dental Hygiene, College of Health Science, Eulji University, Seongnam, Korea.
  3. Clinical Research Center of End Stage Renal Disease in Korea, Daegu, Korea; Department of Epidemiology and Biostatistics, School of Public Health, Seoul National University, Seoul, Korea.
  4. Clinical Research Center of End Stage Renal Disease in Korea, Daegu, Korea; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.
  5. Clinical Research Center of End Stage Renal Disease in Korea, Daegu, Korea; Department of Internal Medicine, Hallym University Hangang Sacred Heart Hospital, Seoul, Korea.
  6. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; Kidney Research Institute, Seoul National University College of Medicine, Seoul, Korea.
  7. Clinical Research Center of End Stage Renal Disease in Korea, Daegu, Korea; Department of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea.
  8. Clinical Research Center of End Stage Renal Disease in Korea, Daegu, Korea; Department of Preventive Medicine, Institute of Health Sciences, Gyeongsang National University of Medicine, Jinju, Korea.
  9. Clinical Research Center of End Stage Renal Disease in Korea, Daegu, Korea; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; N-Bio, Seoul National University, Seoul, Korea.

Abstract

BACKGROUND Health-related quality of life (HRQOL) has recently become an important issue. It reportedly affects morbidity and mortality in patients with end-stage renal disease (ESRD). In this study, we investigated whether early referral and planned dialysis improve the HRQOL and depression of patients with ESRD.

METHODS We prospectively enrolled newly diagnosed patients with ESRD, from 31 hospitals in Korea, who completed questionnaires at 3 months after dialysis. We also got follow-up survey at 1 year after dialysis. To measure HRQOL and depression, Kidney Disease Quality of Life Short Form 36 (KDQOL-36) and Beck's Depression Inventory (BDI) were utilized.

RESULTS A total of 643 patients were analyzed. Referral type did not affect either KDQOL-36 or BDI scores. However, the planned dialysis group showed significantly better scores in 4 of 5 KDQOL-36 domains than did the unplanned group at 3 months after dialysis and partly, the effect was sustained for 1 year after dialysis. The benefit of planned dialysis was significant after adjusting for age, sex, type of dialysis, marital status, educational attainment, occupation, modified Charlson comorbidity index, albumin, and hemoglobin levels. BDI scores were also lower which indicate less depressive mood in planned dialysis group than those in unplanned group both at 3 months and 1 year after dialysis.

CONCLUSIONS Not early referral but planned dialysis improved both the short- and long-term HRQOL and depression of patients with ESRD. Nephrologists should try to help patients to initiate dialysis in a planned manner.

Conflict of interest statement

Competing Interests:The authors have declared that no competing interests exist.

그 밖의 정보
출판 형태
Journal Article, Research Support, Non-U.S. Gov't
저널
PloS one · eISSN 1932-6203
전자 출판
2015-02-23
MeSH
Adult · Aged · Cohort Studies · Depression / psychology · Female · Humans · Kidney Failure, Chronic / psychology / therapy · Male · Middle Aged · Prospective Studies · Quality of Life / psychology · Referral and Consultation · Renal Dialysis / psychology · Republic of Korea · Surveys and Questionnaires · Time Factors
참고문헌
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