BMJ Open. 2018;8(5):e021217.

Association between secondhand smoke exposure and hypertension in never smokers: a cross-sectional survey using data from Korean National Health and Nutritional Examination Survey V, 2010-2012.

, , , , , , , , , ,

제1저자 박영식 · 교신저자 이창훈

PMID 29764884 PMC5961559 DOI 10.1136/bmjopen-2017-021217 IF 2.5 호흡기내과

소속 (10)

Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Korea.
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.
Department of Internal Medicine, Ajou University School of Medicine, Suwon, Korea.
Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.
Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.
Department of Internal Medicine, Chilgok Kyungpook National University School of Medicine, Daegu, Korea.
Department of Internal Medicine, Konkuk University College of Medicine, Seoul, Korea.

Abstract

OBJECTIVES Secondhand smoke (SHS) exposure is associated with cardiovascular disease. This study aims to determine the association between SHS exposure estimated by questionnaire and hypertension in Korean never smokers.

SETTING Korean National Health and Nutrition Examination Survey (KNHANES) V was conducted from 2010 to 2012.

PARTICIPANTS We selected the never smokers aged over 20 years who answered the question about the SHS exposure.

PRIMARY AND SECONDARY MEASURES SHS exposure in both the home and work place was estimated using a self-reporting questionnaire. We investigated the association between SHS exposure and hypertension by using multivariate analysis. And we evaluated the mean systolic and diastolic blood pressure values according to SHS exposure after adjusting for possible confounding factors. All analyses were stratified by women and men.

RESULTS There were 10 532 (women 8987 and men 1545) never smokers. We divided the subjects into three groups according to the amount of SHS exposure: none-group I, <2 hour/day-group II and ≥2 hour/day-group III. Using multivariate analysis, hypertension was more commonly associated with group III than group I in women (adjusted OR 1.50, 95% CI 1.00 to 2.04, p=0.011). Adjusted mean systolic and diastolic blood pressure values in women who were not taking antihypertensive medication were significantly elevated in group III by 2.3 and 1.7 mm Hg, respectively.

CONCLUSION SHS exposure is significantly associated with hypertension in women never smokers.

Keywords

blood pressurehypertensionknhanessecond-hand smoke

Figures

**Figure 1** Flow diagram of study population. KNHANES, Korean National Health and Nutrition Examination Survey.

**Figure 2** Adjusted means of systolic and diastolic blood pressure according to secondhand smoke exposure in women (A and B) and men (C and D) population without antihypertensive treatment. The mean values are adjusted for age, height, weight, waist circumference, serum triglyceride, fasting glucose, education, occupation, alcohol intake and marital status.

그림 출처: PubMed Central 공개 논문 (PMC5961559)

Conflict of interest statement

Competing interests: None declared.

그 밖의 정보