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Sci Rep. 2017;7(1):7542.

Association between Frailty and Hypertension Prevalence, Treatment, and Control in the Elderly Korean Population.

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제1저자 강민구 · 교신저자 김광일

소속 (2)
  1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
  2. Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea. kikim907@snu.ac.kr.

Abstract

Frailty is a common geriatric syndrome characterized by increased risk of disability, hospitalization, and mortality. Hypertension (HTN) is one of the most common chronic medical conditions in the elderly. However, there have been few studies regarding the association between frailty and HTN prevalence, treatment, and control rates. We analyzed data of 4,352 older adults (age ≥ 65 years) from the fifth Korea National Health and Nutrition Examination Survey. We constructed a frailty index based on 42 items and classified participants as robust, pre-frail, or frail. Of the subjects, 2,697 (62.0%) had HTN and 926 (21.3%) had pre-HTN. Regarding frailty status, 721 (16.6%), 1,707 (39.2%), and 1,924 (44.2%) individuals were classified as robust, pre-frail and frail, respectively. HTN prevalence was higher in frail elderly (67.8%) than pre-frail (60.8%) or robust elderly (49.2%) (P < 0.001). Among hypertensive patients, frail elderly were more likely to be treated than pre-frail or robust elderly (P < 0.001), but the proportion of patients whose blood pressure was under control ( < 150/90 mmHg) was lower in frail elderly (P = 0.005). Considering the adverse cardiovascular outcomes associated with frailty, more attention should be paid to the blood pressure control of the frail elderly.

Figures

Figure 1
Figure 1 HTN prevalence, awareness, treatment, and control rate in Korean elderly. 62.0% elderly have HTN, and 80.1% hypertensive elderly were treated; treatment-control rate was 80.8%.
Figure 2
Figure 2 (A) Comparison of HTN prevalence and treatment, and control rate according to frailty status. (*P value < 0.001, † P value = 0.005). HTN prevalence was higher in frail elderly than pre-frail or robust elderly. (P < 0.001) In hypertensive patients, frail elderly are more likely to be treated than pre-frail or robust elderly (P < 0.001). In treated patients, the proportion of patients whose blood pressure was controlled under 150/90 mmHg was significantly lower in frail elderly (P = 0.005). (B) Comparison of SBP and DBP control rate in treated patients according to frailty status. (‡ P value = 0.020, § P value = 0.032). SBP: systolic blood pressure, DBP: diastolic blood pressure. In treated patients, the proportion of patients whose systolic blood pressure was controlled under 150 mmHg was significantly lower in frail elderly (P = 0.020), and the proportion of patients whose diastolic blood pressure was controlled under 90 mmHg was also lower in frail elderly (P = 0.032).
Figure 3
Figure 3 Frailty index (mean) in Korean elderly according to SBP and DBP. SBP: systolic blood pressure, DBP: diastolic blood pressure. U-shape relationship between frailty index and blood pressure was observed.

그림 출처: PubMed Central 공개 논문 (PMC5548733)

Conflict of interest statement

The authors declare that they have no competing interests.

그 밖의 정보
출판 형태
Journal Article
저널
Scientific reports · eISSN 2045-2322
전자 출판
2017-08-08
MeSH
Activities of Daily Living · Aged · Aged, 80 and over · Frail Elderly · Geriatric Assessment / statistics & numerical data · Health Services for the Aged / statistics & numerical data · Hospitalization / statistics & numerical data · Humans · Hypertension / epidemiology / prevention & control / therapy · Nutrition Surveys / statistics & numerical data · Prevalence · Republic of Korea / epidemiology
참고문헌
28편