Dis Colon Rectum. 2018;61(1):43-50.
Clinical Outcomes of Self-Expandable Metal Stents for Malignant Rectal Obstruction.
제1저자 이현정 · 교신저자 박수정
소속 (2)
- Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea.
- Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Abstract
BACKGROUND Self-expandable metal stents are widely used to treat malignant colorectal obstruction. However, data on clinical outcomes of stent placement for rectal obstruction specifically are lacking.
OBJECTIVE We aimed to investigate the clinical outcomes of self-expandable metal stents in malignant rectal obstruction in comparison with those in left colonic obstruction and to identify factors associated with clinical failure and complication.
DESIGN This was a retrospective study.
SETTINGS The study was conducted at a tertiary care center.
PATIENTS Between January 2005 and December 2013, medical charts of patients who underwent stent placement for malignant rectal or left colonic obstruction were reviewed retrospectively.
INTERVENTION Study intervention included self-expandable metal stent placement.
MAIN OUTCOME MEASURES Technical success, clinical success, and complications were measured.
RESULTS Technical success rates for the 2 study groups (rectum vs left colon, 93.5% vs 93.1%; p = 0.86) did not differ significantly; however, the clinical success rate was lower in patients with rectal obstruction (85.4% vs 92.1%; p = 0.02). In addition, the complication rate was higher in patients with rectal obstruction (37.4% vs 25.1%; p = 0.01). Patients with rectal obstruction showed higher rates of obstruction because of extracolonic malignancy (33.8% vs 15.8%; p < 0.001) and stent use for palliation (78.6% vs 56.3%; p < 0.001). Multivariate analysis indicated obstruction attributed to extracolonic malignancy and covered stent usage to be independent risk factors for clinical failure. Factors predictive of complications in the palliative group were total obstruction, obstruction because of extracolonic malignancy, and covered stent usage.
LIMITATIONS This was a retrospective, single-center study.
CONCLUSIONS The efficacy and safety of stent placement for malignant rectal obstruction were comparable with those for left colonic obstruction. However, obstruction attributed to extracolonic malignancy, use of covered stents, and total obstruction negatively impacted clinical outcomes of self-expandable metal stent placement and must be considered by endoscopists. See Video Abstract at http://links.lww.com/DCR/A417.
그 밖의 정보
- 출판 형태
- Journal Article
- 저널
- Diseases of the colon and rectum · eISSN 1530-0358
- MeSH
- Aged · Colonic Neoplasms / complications · Colorectal Neoplasms / complications · Female · Humans · Intestinal Obstruction / etiology / therapy · Male · Middle Aged · Neoplasms / complications · Palliative Care · Prosthesis Implantation* / adverse effects · Rectal Neoplasms / complications · Risk Factors · Self Expandable Metallic Stents* / adverse effects · Treatment Outcome