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Antimicrob Agents Chemother. 2015;59(4):2470-3.

Factors influencing culture positivity in pyogenic vertebral osteomyelitis patients with prior antibiotic exposure.

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제1저자 김충종 · 교신저자 김남중, 박경화

소속 (4)
  1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
  2. Department of Infectious Diseases, Chonnam National University Medical School, Gwang-ju, Republic of Korea.
  3. Department of Infectious Diseases, Chonnam National University Medical School, Gwang-ju, Republic of Korea molder@unitel.co.kr iammedkid@naver.com.
  4. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea molder@unitel.co.kr iammedkid@naver.com.

Abstract

We conducted a retrospective cohort study to evaluate factors influencing tissue culture positivity in patients with pyogenic vertebral osteomyelitis exposed to antibiotics before diagnosis. Tissue culture was positive in 48.3% (28/58) of the patients, and the median antibiotic-free period was 1.5 days (range, 0.7 to 5.7 days). In a multivariate analysis, a higher C-reactive protein (CRP) level (adjusted odds ratio [aOR], 1.18; 95% confidence interval, 1.07 to 1.29) and open surgical biopsy (aOR, 6.33; 95% confidence interval, 1.12 to 35.86) were associated with tissue culture positivity.

Copyright © 2015, American Society for Microbiology. All Rights Reserved.

그 밖의 정보
출판 형태
Journal Article, Research Support, Non-U.S. Gov't
저널
Antimicrobial agents and chemotherapy · eISSN 1098-6596
전자 출판
2015-02-09
MeSH
Aged · Anti-Bacterial Agents / therapeutic use · Bacterial Infections / drug therapy · Biopsy · C-Reactive Protein / metabolism · Cohort Studies · Female · Fever / complications · Humans · Leukocyte Count · Male · Middle Aged · Osteomyelitis / microbiology · Retrospective Studies · Spinal Diseases / microbiology · Spine / microbiology
Substances
Anti-Bacterial Agents · C-Reactive Protein
참고문헌
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