Antimicrob Agents Chemother. 2009;53(8):3582-4.
oqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae.
제1저자 김홍빈 · 교신저자 David C. Hooper
소속 (1)
- Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Abstract
The genes for multidrug efflux pump OqxAB, which is active on fluoroquinolones, were found in human clinical isolates on a plasmid in Escherichia coli and on the chromosome of Klebsiella pneumoniae. IS26-like sequences flanked the plasmid-mediated oqxAB genes, suggesting that they had been mobilized as part of a composite transposon.
그 밖의 정보
- 출판 형태
- Journal Article, Research Support, N.I.H., Extramural
- 저널
- Antimicrobial agents and chemotherapy · eISSN 1098-6596
- 전자 출판
- 2009-06-15
- MeSH
- Anti-Bacterial Agents / pharmacology · Bacterial Proteins / genetics / physiology · DNA Transposable Elements / genetics · Drug Resistance, Bacterial / genetics · Enterobacteriaceae / drug effects / genetics · Escherichia coli / drug effects / genetics · Fluoroquinolones / pharmacology · Humans · Klebsiella pneumoniae / drug effects / genetics · Plasmids / genetics · Sequence Analysis, DNA
- Substances
- Anti-Bacterial Agents · Bacterial Proteins · DNA Transposable Elements · Fluoroquinolones
- 연구비
- NIAID NIH HHS R01 AI043312 · NIAID NIH HHS R01 AI057576 · NIAID NIH HHS R01AI057576 · NIAID NIH HHS R01AI043312
- 참고문헌
- 12편